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Where do you get the body parts from? I mean, there's gotta be an angle there. Are they recovered from the dead? Severed from the living? Donated? Are they essentially magic clones, grown in vats from tissue samples, or, even creepier, within other beings? Clones, I know, age quicker than normal organisms, so maybe there's something in the magic that gives them a limited lifespan?

How much does the magic hold them together, as opposed to biology? Is the magic a one-time deal used to assemble the critter, or does it go
through life lashed together with magic, so that it'd fall apart if the spell is broken? is it somewhere in between?

Are they living, undead, what? If you cut one of them, does it heal, or just ignore the wound? Can they grow? Do they think, or are they just meat-puppets? if they do think, is it with neurons, or is it the spells holding them together? Do they have a pulse? do they need a pulse? Can you kill one by shooting it in the head? in the heart? Maybe they have a back-up heart in case somebody got clever. What organs do they have, anyway? what organs do they need? To what extent are they living organisms, and to what extent are they magic constructs that just happen to be made of flesh? If you, say, hack off their arm, is the arm still animated by the magic holding them together? does it re-attach itself, or function independently, or does it just die like it would with a normal creature?

As to how to defeat them, it's going to vary a lot depending on how they work. Maybe whatever passes for an exorcism in your story-world, perhaps? target the magic, break that up, and the creature falls apart? Maybe they're just really fast, really strong people, resistant to pain and able to take much more damage than a normal person, but will ultimately kick it if you hit them hard enough? Maybe they've got a weak-point you can target, like shooting a Zombie in the brain, and you can take them out easily by going after that, but providing that's intact, they'll keep coming after you no matter how much damage you do? Maybe they've got a limited lifespan, and you can't do much except run and hide until the magic wears off/ their organs fail/etc?

Something just occurred to me- how are they controlled? are they given some sort of task at creation, written into the very spell that holds them together, and they'll follow it single-mindedly? are they puppets, requiring near-constant control from some distant archmage? Do they take orders? How intelligent are they- dog, human, more-than-human? Can they rebel? Could you maybe hijack whatever method is used to control them, either disable them or get them over on your side? If they're smart enough, could you talk one down, could you reason with them?

What do they look like, anyway? Human? Balls of flesh and sinew? Are they tied to any specific anatomy? are they mass-produced? Or can whoever's creating them assemble them in whatever odd and blasphemous shape they want? Either way, maybe there's an anatomical design flaw you can exploit if you know how.


Ahem. Sorry about that. I just love these weird, creepy bits of magio-biotechnology, you know? Hopefully this is more relevant and helpful than the discussion about melons, tumor-monsters, and vampire sperm I hijacked your other thread into.

Another one- poisons. IF they're made of body parts- if they've got some sort of metabolism- then poisons ought to work against them (unless, of course, they've got some sort of magical or natural immunity.) Of course, the trick is getting the poison to them. Probably won't be too easy unless you happen to be a cobra. Ah, well.

EDIT:

Rule 1 of Creation: Anything that can be made can be distroyed.

Nuke the site from orbit. It's the only way to be sure.